What is a repositorium?

The repositorium is a searchable database that provides data on relevant articles from journals, company web pages and web pages of governmental agencies about studies/applications of genome-editing in model plants and agricultural crops in the period January 1996 to May 2018. Search options are article type, technique, plant, traits or free text. The repositorium is based on the systematic map of Dominik Modrzejewski et al., published in the journal environmental evidence. (Download article PDF).

The Arabidopsis catalase triple mutant reveals important roles of catalases and peroxisome-derived signaling in plant development

Typ / Jahr

Journal Article / 2018


Su, Tong; Wang, Pingping; Li, Huijuan; Zhao, Yiwu; Lu, Yao; Dai, Peng; Ren, Tianqi; Wang, Xiaofeng; Li, Xuezhi; Shao, Qun; Zhao, Dazhong; Zhao, Yanxiu; Ma, Changle


qydrogen peroxide (H2O2)is generated in many metabolic processes. As a signaling molecule, H2O2 plays important roles in plant growth and development, as well as environmental stress response. In Arabidopsis, there are three catalase genes, CAT1, CAT2,and CAT3.The encoded catalases are predominately peroxisomal proteins and are critical for scavenging H2O2.Since CAT1 and CAT3 are linked on chromosome 1, it has been almost impossible to generate cat1/3 and cat1/2/3 mutants by traditional genetic tools. In this study, we constructed cat1/3 double mutants and cat1/2/3 triple mutants by CRISPR/Cas9 to investigate the role of catalases. The cat1/ 2/3 triple mutants displayed severe redox disturbance and growth defects under physiological conditions compared with wild-type and the cat2/3 double mutants. Transcriptome analysis showed a more profound transcriptional response in the cat1/2/3 triple mutants compared to the cat2/3 mutants. These differentially expressed genes are involved in plant growth regulation as well as abiotic and biotic stress responses. In addition, expression of OXI1 (OXIDATIVE SIGNAL INDUCIBLE 1)and several MAPK cascade genes were changed dramatically in the catalase triple mutant, suggesting that H2O2 produced in peroxisomes could serve as a peroxisomal retrograde signal.

J. Integr. Plant Biol. (Journal of integrative plant biology)
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ID Corresponding Author
Plant Species GE Technique
Sequence Identifier
Type of Alteration
Progress in Research
Key Topic
818 Zhao, Yanxiu; Ma, Changle
Arabidopsis thaliana CRISPR/Cas9
Growth defects
Basic research
Basic research