Repositorium

What is a repositorium?

The repositorium is a searchable database that provides data on relevant articles from journals, company web pages and web pages of governmental agencies about studies/applications of genome-editing in model plants and agricultural crops in the period January 1996 to May 2018. Search options are article type, technique, plant, traits or free text. The repositorium is based on the systematic map of Dominik Modrzejewski et al., published in the journal environmental evidence. (Download article PDF).

Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion

273

Typ / Jahr

Journal Article / 2017

Autoren

Zong, Yuan; Wang, Yanpeng; Li, Chao; Zhang, Rui; Chen, Kunling; Ran, Yidong; Qiu, Jin-Long; Wang, Daowen; Gao, Caixia

Abstract

Targeted base editing in plants without the need for a foreign DNA donor or double-stranded DNA cleavage would accelerate genome modification and breeding in a wide array of crops. We used a CRISPR-Cas9 nickase-cytidine deaminase fusion to achieve targeted conversion of cytosine to thymine from position 3 to 9 within the protospacer in both protoplasts and regenerated rice, wheat and maize plants at frequencies of up to 43.48%.

Keywords

Sciences -- Biology and Life Sciences -- Bioengineering

Periodical

Nature biotechnology

Periodical Number

Page range

438–440

Volume

DOI

10.1038/nbt.3811

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Techniques

ID	Corresponding Author Country	Plant Species	GE Technique Sequence Identifier	Trait Type of Alteration	Progress in Research Key Topic
659	Caixia Gao China	Zea mays	Base-editing CENH3	No information BE	Basic research Basic research
660	Caixia Gao China	Oryza sativa	Base-editing NRT1	increased nitrogene use efficience BE	Basic research Basic research
661	Caixia Gao China	Oryza sativa	Base-editing SPL14	Plant hight BE	Basic research Basic research
662	Caixia Gao China	Oryza sativa	Base-editing CDC48	senescence and cell death BE	Basic research Basic research
663	Caixia Gao China	Triticum aestivum	Base-editing LOX2	seed storability BE	Basic research Basic research