Repositorium

What is a repositorium?

The repositorium is a searchable database that provides data on relevant articles from journals, company web pages and web pages of governmental agencies about studies/applications of genome-editing in model plants and agricultural crops in the period January 1996 to May 2018. Search options are article type, technique, plant, traits or free text. The repositorium is based on the systematic map of Dominik Modrzejewski et al., published in the journal environmental evidence. (Download article PDF).

Histone H2AX and the small RNA pathway modulate both non-homologous end-joining and homologous recombination in plants


Typ / Jahr

Journal Article / 2016

Autoren

Qi, Yiping; Zhang, Yong; Baller, Joshua A.; Voytas, Daniel F.

Abstract

Using a zinc finger nuclease (ZFN) that creates a site-specific DNA double-strand break (DSB) at the endogenous ADH1 locus, we provide genetic evidence that histone H2AX and DSB-induced small RNAs modulate DNA repair by both non-homologous end-joining (NHEJ) and homologous recombination (HR) in the model plant Arabidopsis thaliana.

Keywords
Arabidopsis thaliana; DNA double-strand break (DSB) repair; H2AX; Small RNA; zinc finger nuclease (ZFN)
Periodical
Mutation research
Periodical Number
Page range
9–14
Volume
783
DOI
10.1016/j.mrfmmm.2015.12.002

Techniques

ID Corresponding Author
Country
Plant Species GE Technique
Sequence Identifier
Trait
Type of Alteration
Progress in Research
Key Topic
373 Qi, Yiping
USA
Arabidopsis thaliana Zinc-finger nucleases
ADH1
Allyl alcohol resistance
SDN1
Basic research
Basic research
374 Qi, Yiping
USA
Arabidopsis thaliana Zinc-finger nucleases
ADH1
Allyl alcohol resistance
SDN3
Basic research
Basic research